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Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion
OPA1, a large GTPase of the dynamin superfamily, mediates fusion of the mitochondrial inner membranes, regulates cristae morphology, and maintains respiratory chain function. Inner membrane–anchored long forms of OPA1 (l-OPA1) are proteolytically processed by the OMA1 or YME1L proteases, acting at c...
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| Publicado no: | Mol Biol Cell |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8120690/ https://ncbi.nlm.nih.gov/pubmed/33237841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E20-09-0605 |
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