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Emerging therapies for inv(16) AML
The core binding factor composed of CBFβ and RUNX subunits plays a critical role in most hematopoietic lineages and is deregulated in acute myeloid leukemia (AML). The fusion oncogene CBFβ-SMMHC expressed in AML with the chromosome inversion inv(16)(p13q22) acts as a driver oncogene in hematopoietic...
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| 出版年: | Blood |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2021
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8120144/ https://ncbi.nlm.nih.gov/pubmed/33821975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020009933 |
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