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p27 controls autophagic vesicle trafficking in glucose-deprived cells via the regulation of ATAT1-mediated microtubule acetylation

The cyclin-dependent kinase inhibitor p27(Kip1) (p27) has been involved in promoting autophagy and survival in conditions of metabolic stress. While the signaling cascade upstream of p27 leading to its cytoplasmic localization and autophagy induction has been extensively studied, how p27 stimulates...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Nowosad, Ada, Creff, Justine, Jeannot, Pauline, Culerrier, Raphael, Codogno, Patrice, Manenti, Stephane, Nguyen, Laurent, Besson, Arnaud
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119952/
https://ncbi.nlm.nih.gov/pubmed/33986251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03759-9
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