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p27 controls autophagic vesicle trafficking in glucose-deprived cells via the regulation of ATAT1-mediated microtubule acetylation

The cyclin-dependent kinase inhibitor p27(Kip1) (p27) has been involved in promoting autophagy and survival in conditions of metabolic stress. While the signaling cascade upstream of p27 leading to its cytoplasmic localization and autophagy induction has been extensively studied, how p27 stimulates...

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Vydáno v:Cell Death Dis
Hlavní autoři: Nowosad, Ada, Creff, Justine, Jeannot, Pauline, Culerrier, Raphael, Codogno, Patrice, Manenti, Stephane, Nguyen, Laurent, Besson, Arnaud
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119952/
https://ncbi.nlm.nih.gov/pubmed/33986251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03759-9
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