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IFN-β reduces NRP-1 expression on human cord blood monocytes and inhibits VEGF-induced chemotaxis
IFN-β directly downregulates NRP-1 expression in monocytes, inhibiting monocyte chemotaxis toward a VEGF enriched environment. Type I interferons (IFNs) inhibit angiogenesis, the sprouting of new blood vessels, during tissue development, remodeling, and tumor growth. One of the major targets type I...
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| Publicat a: | Cytokine |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8119361/ https://ncbi.nlm.nih.gov/pubmed/33858750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2021.155519 |
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