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Human Umbilical Cord Blood-Derived Monocytes Improve Cognitive Deficits and Reduce Amyloid-β Pathology in PSAPP Mice

Alzheimer’s disease (AD) is the fourth major cause of mortality in the elderly in the US and the leading cause of dementia worldwide. While pharmacological targets have been discovered, there are no true disease-modifying therapies. We have recently discovered that multiple low-dose infusions of hum...

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Detalhes bibliográficos
Publicado no:Cell Transplant
Main Authors: Darlington, Donna, Li, Song, Hou, Huayan, Habib, Ahsan, Tian, Jun, Gao, Yang, Ehrhart, Jared, Sanberg, Paul R, Sawmiller, Darrell, Giunta, Brian, Mori, Takashi, Tan, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5822726/
https://ncbi.nlm.nih.gov/pubmed/26230612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096368915X688894
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