Llwytho...

Polycomb gene silencing mechanisms: PRC2 chromatin targeting, H3K27me3 “readout” and phase separation-based compaction

Modulation of chromatin structure and/or modification by Polycomb repressive complexes (PRCs) provides an important means to partition the genome into functionally distinct subdomains and to regulate the activity of the underlying genes. Both the enzymatic activity of PRC2 and its chromatin recruitm...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Trends Genet
Prif Awduron: Guo, Yiran, Zhao, Shuai, Wang, Gang Greg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119337/
https://ncbi.nlm.nih.gov/pubmed/33494958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2020.12.006
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