Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies

Human pluripotent stem cells (PSCs), which are composed of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), provide an opportunity to advance cardiac cell therapy–based clinical trials. However, an important hurdle that must be overcome is the risk of teratoma formation after...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Chour, Tony, Tian, Lei, Lau, Edward, Thomas, Dilip, Itzhaki, Ilanit, Malak, Olfat, Zhang, Joe Z., Qin, Xulei, Wardak, Mirwais, Liu, Yonggang, Chandy, Mark, Black, Katelyn E., Lam, Maggie P.Y., Neofytou, Evgenios, Wu, Joseph C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2021
Assuntos:
Technical Advance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119193/
https://ncbi.nlm.nih.gov/pubmed/33830086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142000
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