Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction

Non-human primates (NHPs) can serve as a human-like model to study cell therapy using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). However, whether the efficacy of NHP and human iPSC-CMs is mechanistically similar remains unknown. To examine this, RNU rats received intramyocardia...

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Pubblicato in:Stem Cell Reports
Autori principali: Zhao, Xin, Chen, Haodong, Xiao, Dan, Yang, Huaxiao, Itzhaki, Ilanit, Qin, Xulei, Chour, Tony, Aguirre, Aitor, Lehmann, Kim, Kim, Youngkyun, Shukla, Praveen, Holmström, Alexandra, Zhang, Joe Z., Zhuge, Yan, Ndoye, Babacar C., Zhao, Mingtao, Neofytou, Evgenios, Zimmermann, Wolfram-Hubertus, Jain, Mohit, Wu, Joseph C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5830958/
https://ncbi.nlm.nih.gov/pubmed/29398480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2018.01.002
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