Method for selective ablation of undifferentiated human pluripotent stem cell populations for cell-based therapies

Human pluripotent stem cells (PSCs), which are composed of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs), provide an opportunity to advance cardiac cell therapy–based clinical trials. However, an important hurdle that must be overcome is the risk of teratoma formation after...

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Bibliografiset tiedot
Julkaisussa:JCI Insight
Päätekijät: Chour, Tony, Tian, Lei, Lau, Edward, Thomas, Dilip, Itzhaki, Ilanit, Malak, Olfat, Zhang, Joe Z., Qin, Xulei, Wardak, Mirwais, Liu, Yonggang, Chandy, Mark, Black, Katelyn E., Lam, Maggie P.Y., Neofytou, Evgenios, Wu, Joseph C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Clinical Investigation 2021
Aiheet:
Technical Advance
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119193/
https://ncbi.nlm.nih.gov/pubmed/33830086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.142000
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