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Cell death–associated lipid droplet protein CIDE-A is a noncanonical marker of endoplasmic reticulum stress

Secretory protein misfolding has been linked to ER stress and cell death. We expressed a TG(rdw) transgene encoding TG-G(2298)R, a misfolded mutant thyroglobulin reported to be linked to thyroid cell death. When the TG(rdw) transgene was expressed at low level in thyrocytes of TG(cog/cog) mice that...

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Détails bibliographiques
Publié dans:JCI Insight
Auteurs principaux: Morishita, Yoshiaki, Kellogg, Aaron P., Larkin, Dennis, Chen, Wei, Vadrevu, Suryakiran, Satin, Leslie, Liu, Ming, Arvan, Peter
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119190/
https://ncbi.nlm.nih.gov/pubmed/33661766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.143980
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