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AKT Inhibitors: New Weapons in the Fight Against Breast Cancer?
The serine/threonine kinase AKT is a key component of the PI3K/AKT/mTOR signaling pathway as it exerts a pivotal role in cell growth, proliferation, survival, and metabolism. Deregulation of this pathway is a common event in breast cancer including hormone receptor-positive (HR+) disease, HER2-ampli...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8118639/ https://ncbi.nlm.nih.gov/pubmed/33995085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.662232 |
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