Activation of the IGF Axis in Thyroid Cancer: Implications for Tumorigenesis and Treatment

The Insulin-like growth factor (IGF) axis is one of the best-established drivers of thyroid transformation, as thyroid cancer cells overexpress both IGF ligands and their receptors. Thyroid neoplasms encompass distinct clinical and biological entities as differentiated thyroid carcinomas (DTC)—compr...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Manzella, Livia, Massimino, Michele, Stella, Stefania, Tirrò, Elena, Pennisi, Maria Stella, Martorana, Federica, Motta, Gianmarco, Vitale, Silvia Rita, Puma, Adriana, Romano, Chiara, Di Gregorio, Sandra, Russo, Marco, Malandrino, Pasqualino, Vigneri, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6651760/
https://ncbi.nlm.nih.gov/pubmed/31269742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20133258
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