Human DICER helicase domain recruits PKR and modulates its antiviral activity

The antiviral innate immune response mainly involves type I interferon (IFN) in mammalian cells. The contribution of the RNA silencing machinery remains to be established, but several recent studies indicate that the ribonuclease DICER can generate viral siRNAs in specific conditions. It has also be...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Montavon, Thomas C., Baldaccini, Morgane, Lefèvre, Mathieu, Girardi, Erika, Chane-Woon-Ming, Béatrice, Messmer, Mélanie, Hammann, Philippe, Chicher, Johana, Pfeffer, Sébastien
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8118307/
https://ncbi.nlm.nih.gov/pubmed/33984068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009549
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