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Generating Stereodiversity: Diastereoselective Fluorination and Highly Diastereoselective Epimerization of α-Amino Acid Building Blocks

Diastereoselective fluorination of N-Boc (R) and (S)-2,2-dimethyl-4-((arylsulfonyl)methyl)oxazolidines, and a previously unknown diastereoselective epimerization at the fluorine-bearing carbon atom alpha to the sulfone was realized. Diastereoselectivities of both reactions were excellent for benzoth...

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Dades bibliogràfiques
Publicat a:Org Lett
Autors principals: Wei, Wei, Khangarot, Rama Kanwar, Stahl, Lothar, Veresmortean, Cristina, Pradhan, Padmanava, Yang, Lijia, Zajc, Barbara
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117975/
https://ncbi.nlm.nih.gov/pubmed/29856640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.8b01358
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