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Antigen-dependent interactions between regulatory B cells and T cells at the T:B border inhibit subsequent T cell interactions with DCs

IL-10+ regulatory B cells (Bregs) inhibit immune responses in various settings. While Bregs appear to inhibit inflammatory cytokine expression by CD4+ T cells and innate immune cells, their impact on CD8+ T cells is contradictory. Moreover, it remains unclear, which effects of Bregs are direct. The...

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Библиографические подробности
Опубликовано в: :Am J Transplant
Главные авторы: Mohib, Kanishka, Cherukuri, Aravind, Zhou, Yu, Ding, Qing, Watkins, Simon C., Rothstein, David M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117747/
https://ncbi.nlm.nih.gov/pubmed/31355483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.15546
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