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Regulatory B cells: TIM‐1, transplant tolerance, and rejection

Regulatory B cells (Bregs) ameliorate autoimmune disease and prevent allograft rejection. Conversely, they hinder effective clearance of pathogens and malignancies. Breg activity is mainly attributed to IL‐10 expression, but also utilizes additional regulatory mechanisms such as TGF‐β, FasL, IL‐35,...

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Detalhes bibliográficos
Publicado no:Immunol Rev
Main Authors: Cherukuri, Aravind, Mohib, Kanishka, Rothstein, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7968891/
https://ncbi.nlm.nih.gov/pubmed/33484008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12933
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