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Structure of the human Mediator-bound transcription pre-initiation complex

Eukaryotic transcription requires the assembly of a multi-subunit pre-initiation complex (PIC) comprised of RNA polymerase II (Pol II) and the general transcription factors. The co-activator Mediator is recruited by transcription factors, facilitates the assembly of the PIC, and stimulates phosphory...

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Bibliografske podrobnosti
izdano v:Science
Main Authors: Abdella, R., Talyzina, A., Chen, S., Inouye, C. J., Tjian, R., He, Y.
Format: Artigo
Jezik:Inglês
Izdano: 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117670/
https://ncbi.nlm.nih.gov/pubmed/33707221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abg3074
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