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Germline risk of clonal haematopoiesis
Clonal haematopoiesis (CH) is a common, age-related expansion of blood cells with somatic mutations that is associated with an increased risk of haematological malignancies, cardiovascular disease and all-cause mortality. CH may be caused by point mutations in genes associated with myeloid neoplasms...
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| Опубликовано в: : | Nat Rev Genet |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8117131/ https://ncbi.nlm.nih.gov/pubmed/33986496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41576-021-00356-6 |
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