Full spectrum of clonal haematopoiesis‐driver mutations in chronic heart failure and their associations with mortality

AIMS: Somatic mutations in haematopoietic stem cells can lead to the clonal expansion of mutated blood cells, known as clonal haematopoiesis (CH). Mutations in the most prevalent driver genes DNMT3A and TET2 with a variant allele frequency (VAF) ≥ 2% have been associated with atherosclerosis and chr...

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Bibliografische gegevens
Gepubliceerd in:ESC Heart Fail
Hoofdauteurs: Kiefer, Katharina C., Cremer, Sebastian, Pardali, Evangelia, Assmus, Birgit, Abou‐El‐Ardat, Khalil, Kirschbaum, Klara, Dorsheimer, Lena, Rasper, Tina, Berkowitsch, Alexander, Serve, Hubert, Dimmeler, Stefanie, Zeiher, Andreas M., Rieger, Michael A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
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Original Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120376/
https://ncbi.nlm.nih.gov/pubmed/33779075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.13297
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