Full spectrum of clonal haematopoiesis‐driver mutations in chronic heart failure and their associations with mortality

AIMS: Somatic mutations in haematopoietic stem cells can lead to the clonal expansion of mutated blood cells, known as clonal haematopoiesis (CH). Mutations in the most prevalent driver genes DNMT3A and TET2 with a variant allele frequency (VAF) ≥ 2% have been associated with atherosclerosis and chr...

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Pubblicato in:ESC Heart Fail
Autori principali: Kiefer, Katharina C., Cremer, Sebastian, Pardali, Evangelia, Assmus, Birgit, Abou‐El‐Ardat, Khalil, Kirschbaum, Klara, Dorsheimer, Lena, Rasper, Tina, Berkowitsch, Alexander, Serve, Hubert, Dimmeler, Stefanie, Zeiher, Andreas M., Rieger, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Original Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120376/
https://ncbi.nlm.nih.gov/pubmed/33779075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.13297
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