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The Earliest T-Precursors in the Mouse Embryo Are Susceptible to Leukemic Transformation

Acute lymphoblastic leukemia (ALL) is the most common malignancy in pediatric patients. About 10–15% of pediatric ALL belong to T-cell ALL (T-ALL), which is characterized by aggressive expansion of immature T-lymphoblasts and is categorized as high-risk leukemia. Leukemia initiating cells represent...

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Publié dans:Front Cell Dev Biol
Auteurs principaux: Ding, Jixin, Cardoso, Angelo A., Yoshimoto, Momoko, Kobayashi, Michihiro
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2021
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117020/
https://ncbi.nlm.nih.gov/pubmed/33996794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.634151
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