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Functional B-1 progenitor cells are present in the hematopoietic stem cell-deficient embryo and depend on Cbfβ for their development

The fetal liver is a major hematopoietic site containing progenitor cells that give rise to nearly all blood cells, including B-1 cells. Because the fetal liver is not a de novo site of hematopoietic stem cell (HSC) or progenitor-cell emergence, it must be seeded by yolk sac (YS)-derived erythromyel...

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Detalhes bibliográficos
Main Authors: Kobayashi, Michihiro, Shelley, W. Christopher, Seo, Wooseok, Vemula, Sasidhar, Lin, Yang, Liu, Yan, Kapur, Reuben, Taniuchi, Ichiro, Yoshimoto, Momoko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143017/
https://ncbi.nlm.nih.gov/pubmed/25092306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1407370111
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