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What do the lineage tracing studies tell us? Consideration for hematopoietic stem cell origin, dynamics, and leukemia-initiating cells

The recent advance of technologies enables us to trace the cell fate in vivo by marking the cells that express the gene of interest or by barcoding them at a single cell level. Various tamoxifen-inducible Cre-recombinase mice combined with Rosa-floxed lines are utilized. In this review, with the res...

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Detalhes bibliográficos
Publicado no:Int J Hematol
Main Authors: Portilho, Nathalia Azevedo, Kobayashi, Michihiro, Yoshimoto, Momoko
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450395/
https://ncbi.nlm.nih.gov/pubmed/30264284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12185-018-2537-9
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