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Fusogenic oncolytic vaccinia virus enhances systemic antitumor immune response by modulating the tumor microenvironment
Oncolytic viruses induce antitumor immunity following direct viral oncolysis. However, their therapeutic effects are limited in distant untreated tumors because their antitumor function depends on indirect antitumor immunity. Here, we generated a novel fusogenic oncolytic vaccinia virus (FUVAC) and...
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| Publicado no: | Mol Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Gene & Cell Therapy
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8116573/ https://ncbi.nlm.nih.gov/pubmed/33348052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.12.024 |
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