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Neurotropic influenza A virus infection causes prion protein misfolding into infectious prions in neuroblastoma cells
Misfolding of the cellular prion protein, PrP(C), into the amyloidogenic isoform, PrP(Sc), which forms infectious protein aggregates, the so-called prions, is a key pathogenic event in prion diseases. No pathogens other than prions have been identified to induce misfolding of PrP(C) into PrP(Sc) and...
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| 發表在: | Sci Rep |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8115602/ https://ncbi.nlm.nih.gov/pubmed/33980968 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89586-6 |
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