Prion protein protects mice from lethal infection with influenza A viruses

The cellular prion protein, designated PrP(C), is a membrane glycoprotein expressed abundantly in brains and to a lesser extent in other tissues. Conformational conversion of PrP(C) into the amyloidogenic isoform is a key pathogenic event in prion diseases. However, the physiological functions of Pr...

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Podrobná bibliografie
Vydáno v:PLoS Pathog
Hlavní autoři: Chida, Junji, Hara, Hideyuki, Yano, Masashi, Uchiyama, Keiji, Das, Nandita Rani, Takahashi, Etsuhisa, Miyata, Hironori, Tomioka, Yukiko, Ito, Toshihiro, Kido, Hiroshi, Sakaguchi, Suehiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5953499/
https://ncbi.nlm.nih.gov/pubmed/29723291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007049
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