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Enabling highly (R)-enantioselective epoxidation of styrene by engineering unique non-natural P450 peroxygenases

Unlike the excellent (S)-enantioselective epoxidation of styrene performed by natural styrene monooxygenases (ee > 99%), the (R)-enantioselective epoxidation of styrene has not yet achieved a comparable efficiency using natural or engineered oxidative enzymes. This report describes the H(2)O(2)-d...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Zhao, Panxia, Chen, Jie, Ma, Nana, Chen, Jingfei, Qin, Xiangquan, Liu, Chuanfei, Yao, Fuquan, Yao, Lishan, Jin, Longyi, Cong, Zhiqi
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115292/
https://ncbi.nlm.nih.gov/pubmed/34084428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00317h
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