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Human monocyte-derived type 1 and 2 macrophages recognize Ara h 1, a major peanut allergen, by different mechanisms

Evidence has suggested that major peanut allergen Ara h 1 activates dendritic cells (DCs) via interaction with DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin), a C-type lectin receptor, and contributes to development of peanut allergy. Since macrophages, as...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Krause, Maren, Crauwels, Peter, Blanco-Pérez, Frank, Globisch, Martin, Wangorsch, Andrea, Henle, Thomas, Lidholm, Jonas, van Zandbergen, Ger, Vieths, Stefan, Scheurer, Stephan, Toda, Masako
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8115286/
https://ncbi.nlm.nih.gov/pubmed/33980880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89402-1
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