Population Pharmacokinetics and Initial Dose Optimization of Sirolimus Improving Drug Blood Level for Seizure Control in Pediatric Patients With Tuberous Sclerosis Complex

The purposes of this study were to explore the population pharmacokinetics and initial dose optimization of sirolimus improving drug blood level for seizure control in pediatric patients with tuberous sclerosis complex (TSC). Eighty pediatric patients diagnosed with TSC-related epilepsy were include...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Pharmacol
Päätekijät: Chen, Xiao, Wang, Dongdong, Zhu, Lin, Lu, Jinmiao, Huang, Yidie, Wang, Guangfei, Zhu, Yiqing, Ye, Qiaofeng, Wang, Yi, Xu, Hong, Li, Zhiping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2021
Aiheet:
Pharmacology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114543/
https://ncbi.nlm.nih.gov/pubmed/33995061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.647232
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