Population Pharmacokinetics and Initial Dose Optimization of Sirolimus Improving Drug Blood Level for Seizure Control in Pediatric Patients With Tuberous Sclerosis Complex

The purposes of this study were to explore the population pharmacokinetics and initial dose optimization of sirolimus improving drug blood level for seizure control in pediatric patients with tuberous sclerosis complex (TSC). Eighty pediatric patients diagnosed with TSC-related epilepsy were include...

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Detaylı Bibliyografya
Yayımlandı:Front Pharmacol
Asıl Yazarlar: Chen, Xiao, Wang, Dongdong, Zhu, Lin, Lu, Jinmiao, Huang, Yidie, Wang, Guangfei, Zhu, Yiqing, Ye, Qiaofeng, Wang, Yi, Xu, Hong, Li, Zhiping
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Pharmacology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8114543/
https://ncbi.nlm.nih.gov/pubmed/33995061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.647232
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