Sirolimus for Angiomyolipoma in Tuberous Sclerosis Complex or Lymphangioleiomyomatosis

BACKGROUND: Angiomyolipomas in patients with the tuberous sclerosis complex or sporadic lymphangioleiomyomatosis are associated with mutations in tuberous sclerosis genes resulting in constitutive activation of the mammalian target of rapamycin (mTOR). The drug sirolimus suppresses mTOR signaling. M...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Bissler, John J., McCormack, Francis X., Young, Lisa R., Elwing, Jean M., Chuck, Gail, Leonard, Jennifer M., Schmithorst, Vincent J., Laor, Tal, Brody, Alan S., Bean, Judy, Salisbury, Shelia, Franz, David N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3398441/
https://ncbi.nlm.nih.gov/pubmed/18184959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa063564
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