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Sensitive FRET Biosensor Reveals Fyn Kinase Regulation by Submembrane Localization
Fyn kinase plays crucial roles in hematology and T cell signaling; however, there are currently limited tools to visualize the dynamic Fyn activity in live cells. Here we developed and characterized a highly sensitive Fyn biosensor based on fluorescence resonance energy transfer (FRET) to monitor Fy...
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| Publicado no: | ACS Sens |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8114461/ https://ncbi.nlm.nih.gov/pubmed/30588803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acssensors.8b00896 |
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