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Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells

Previous studies with various Src family kinase biosensors showed that the nuclear kinase activities are much suppressed compared to those in the cytosol, suggesting that these kinases are regulated differently in the nucleus and in the cytosol. In this study, using Fyn as an example, we first engin...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Huang, Ziliang, Ouyang, Mingxing, Lu, Shaoying, Wang, Yingxiao, Peng, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225052/
https://ncbi.nlm.nih.gov/pubmed/32198118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.03.015
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