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Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells

Previous studies with various Src family kinase biosensors showed that the nuclear kinase activities are much suppressed compared to those in the cytosol, suggesting that these kinases are regulated differently in the nucleus and in the cytosol. In this study, using Fyn as an example, we first engin...

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Podrobná bibliografie
Vydáno v:J Mol Biol
Hlavní autoři: Huang, Ziliang, Ouyang, Mingxing, Lu, Shaoying, Wang, Yingxiao, Peng, Qin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7225052/
https://ncbi.nlm.nih.gov/pubmed/32198118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.03.015
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