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Optogenetic Control for Investigating Subcellular Localization of Fyn Kinase Activity in Single Live Cells
Previous studies with various Src family kinase biosensors showed that the nuclear kinase activities are much suppressed compared to those in the cytosol, suggesting that these kinases are regulated differently in the nucleus and in the cytosol. In this study, using Fyn as an example, we first engin...
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| 發表在: | J Mol Biol |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7225052/ https://ncbi.nlm.nih.gov/pubmed/32198118 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2020.03.015 |
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