In vivo genome editing in single mammalian brain neurons through CRISPR-Cas9 and cytosine base editors

Gene manipulation is a useful approach for understanding functions of genes and is important for investigating basic mechanisms of brain function on the level of single neurons and circuits. Despite the development and the wide range of applications of CRISPR-Cas9 and base editors (BEs), their imple...

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Detalles Bibliográficos
Publicado en:Comput Struct Biotechnol J
Main Authors: Song, Beomjong, Kang, Chan Young, Han, Jun Hee, Kano, Masanobu, Konnerth, Arthur, Bae, Sangsu
Formato: Artigo
Idioma:Inglês
Publicado: Research Network of Computational and Structural Biotechnology 2021
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113754/
https://ncbi.nlm.nih.gov/pubmed/34025938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.051
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