In vivo genome editing in single mammalian brain neurons through CRISPR-Cas9 and cytosine base editors

Gene manipulation is a useful approach for understanding functions of genes and is important for investigating basic mechanisms of brain function on the level of single neurons and circuits. Despite the development and the wide range of applications of CRISPR-Cas9 and base editors (BEs), their imple...

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Bibliografiska uppgifter
I publikationen:Comput Struct Biotechnol J
Huvudupphovsmän: Song, Beomjong, Kang, Chan Young, Han, Jun Hee, Kano, Masanobu, Konnerth, Arthur, Bae, Sangsu
Materialtyp: Artigo
Språk:Inglês
Publicerad: Research Network of Computational and Structural Biotechnology 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113754/
https://ncbi.nlm.nih.gov/pubmed/34025938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2021.04.051
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