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CopyCatchers are versatile active genetic elements that detect and quantify inter-homolog somatic gene conversion
CRISPR-based active genetic elements, or gene-drives, copied via homology-directed repair (HDR) in the germline, are transmitted to progeny at super-Mendelian frequencies. Active genetic elements also can generate widespread somatic mutations, but the genetic basis for such phenotypes remains uncert...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8113449/ https://ncbi.nlm.nih.gov/pubmed/33976171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-22927-1 |
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