[(11)C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates

PURPOSE: Deposition of misfolded alpha-synuclein (αSYN) aggregates in the human brain is one of the major hallmarks of synucleinopathies. However, a target-specific tracer to detect pathological aggregates of αSYN remains lacking. Here, we report the development of a positron emission tomography (PE...

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Bibliografiset tiedot
Julkaisussa:Eur J Nucl Med Mol Imaging
Päätekijät: Kuebler, Laura, Buss, Sabrina, Leonov, Andrei, Ryazanov, Sergey, Schmidt, Felix, Maurer, Andreas, Weckbecker, Daniel, Landau, Anne M., Lillethorup, Thea P., Bleher, Daniel, Saw, Ran Sing, Pichler, Bernd J., Griesinger, Christian, Giese, Armin, Herfert, Kristina
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Berlin Heidelberg 2020
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Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113290/
https://ncbi.nlm.nih.gov/pubmed/33369690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-020-05133-x
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