The interferon-stimulated exosomal hACE2 potently inhibits SARS-CoV-2 replication through competitively blocking the virus entry

Since the outbreak of coronavirus disease 2019 (COVID-19), it has become a global pandemic. The spike (S) protein of etiologic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) specifically recognizes human angiotensin-converting enzyme 2 (hACE2) as its receptor, which is recently identif...

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Detalhes bibliográficos
Publicado no:Signal Transduct Target Ther
Main Authors: Zhang, Junsong, Huang, Feng, Xia, Baijin, Yuan, Yaochang, Yu, Fei, Wang, Guanwen, Chen, Qianyu, Wang, Qian, Li, Yuzhuang, Li, Rong, Song, Zheng, Pan, Ting, Chen, Jingliang, Lu, Gen, Zhang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8113286/
https://ncbi.nlm.nih.gov/pubmed/33980808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-021-00604-5
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