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Synthesis of 10-O-aryl-substituted berberine derivatives by Chan–Evans–Lam coupling and investigation of their DNA-binding properties
Eleven novel 10-O-aryl-substituted berberrubine and berberine derivatives were synthesized by the Cu(2+)-catalyzed Chan–Evans–Lam coupling of berberrubine with arylboronic acids and subsequent 9-O-methylation. The reaction is likely introduced by the Cu(2+)-induced demethylation of berberrubine and...
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| Publicado en: | Beilstein J Org Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Beilstein-Institut
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8111429/ https://ncbi.nlm.nih.gov/pubmed/34025807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.81 |
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