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Synthesis of 10-O-aryl-substituted berberine derivatives by Chan–Evans–Lam coupling and investigation of their DNA-binding properties

Eleven novel 10-O-aryl-substituted berberrubine and berberine derivatives were synthesized by the Cu(2+)-catalyzed Chan–Evans–Lam coupling of berberrubine with arylboronic acids and subsequent 9-O-methylation. The reaction is likely introduced by the Cu(2+)-induced demethylation of berberrubine and...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Beilstein J Org Chem
मुख्य लेखकों: Wickhorst, Peter Jonas, Blachnik, Mathilda, Lagumdzija, Denisa, Ihmels, Heiko
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Beilstein-Institut 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111429/
https://ncbi.nlm.nih.gov/pubmed/34025807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.17.81
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