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Selective deletion of connective tissue growth factor attenuates experimentally-induced pulmonary fibrosis and pulmonary arterial hypertension

Connective tissue growth factor (CTGF, CCN2) is a matricellular protein which plays key roles in normal mammalian development and in tissue homeostasis and repair. In pathological conditions, dysregulated CCN2 has been associated with cancer, cardiovascular disease, and tissue fibrosis. In this stud...

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發表在:Int J Biochem Cell Biol
Main Authors: Tam, Angela Y.Y., Horwell, Amy L., Trinder, Sarah L., Khan, Korsa, Xu, Shiwen, Ong, Voon, Denton, Christopher P., Norman, Jill T., Holmes, Alan M., Bou-Gharios, George, Abraham, David J.
格式: Artigo
語言:Inglês
出版: Elsevier 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111417/
https://ncbi.nlm.nih.gov/pubmed/33662577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2021.105961
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