Failed Degradation of JunB Contributes to Overproduction of Type I Collagen and Development of Dermal Fibrosis in Patients With Systemic Sclerosis

OBJECTIVE: The excessive deposition of extracellular matrix, including type I collagen, is a key aspect in the pathogenesis of connective tissue diseases such as systemic sclerosis (SSc; scleroderma). To further our understanding of the mechanisms governing the dysregulation of type I collagen produ...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Ponticos, Markella, Papaioannou, Ioannis, Xu, Shiwen, Holmes, Alan M, Khan, Korsa, Denton, Christopher P, Bou-Gharios, George, Abraham, David J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2015
Assuntos:
Systemic Sclerosis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312903/
https://ncbi.nlm.nih.gov/pubmed/25303440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38897
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados