Activation of GSK3 Prevents Termination of TNF-Induced Signaling

BACKGROUND: Termination of TNF-induced signaling plays a key role in the resolution of inflammation with dysregulations leading to severe pathophysiological conditions (sepsis, chronic inflammatory disease, cancer). Since a recent phospho-proteome analysis in human monocytes suggested GSK3 as a rele...

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Bibliographic Details
Published in:J Inflamm Res
Main Authors: Welz, Bastian, Bikker, Rolf, Hoffmeister, Leonie, Diekmann, Mareike, Christmann, Martin, Brand, Korbinian, Huber, René
Format: Artigo
Language:Inglês
Published: Dove 2021
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8111165/
https://ncbi.nlm.nih.gov/pubmed/33986607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S300806
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