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TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms

Tumor necrosis factor (TNF) tolerance in monocytes and macrophages means that preexposure to TNF reduces the sensitivity in these cells to a subsequent restimulation with this cytokine. Differential effects arise following preincubation with both low and high doses of TNF resulting in absolute as we...

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Pubblicato in:J Immunol Res
Autori principali: Huber, René, Bikker, Rolf, Welz, Bastian, Christmann, Martin, Brand, Korbinian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698820/
https://ncbi.nlm.nih.gov/pubmed/29250561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9570129
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