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I(2) imidazoline receptor modulation protects aged SAMP8 mice against cognitive decline by suppressing the calcineurin pathway
Brain aging and dementia are current problems that must be solved. The levels of imidazoline 2 receptors (I(2)-IRs) are increased in the brain in Alzheimer’s disease (AD) and other neurodegenerative diseases. We tested the action of the specific and selective I(2)-IR ligand B06 in a mouse model of a...
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| הוצא לאור ב: | GeroScience |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Springer International Publishing
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8110656/ https://ncbi.nlm.nih.gov/pubmed/33128688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00281-2 |
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