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Amelioration of BPSD-Like Phenotype and Cognitive Decline in SAMP8 Mice Model Accompanied by Molecular Changes after Treatment with I(2)-Imidazoline Receptor Ligand MCR5

Behavioural and psychological symptoms of dementia (BPSD), including fear-anxiety- and depressive-like behaviour, are present in Alzheimer’s disease (AD), together with memory decline. I(2)-imidazoline receptors (I(2)-IRs) have been associated with neuropsychiatric and neurodegenerative disorders, f...

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Bibliografski detalji
Izdano u:Pharmaceutics
Glavni autori: Vasilopoulou, Foteini, Bagan, Andrea, Rodriguez-Arevalo, Sergio, Escolano, Carmen, Griñán-Ferré, Christian, Pallàs, Mercè
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7285228/
https://ncbi.nlm.nih.gov/pubmed/32456135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12050475
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