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The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats

Diabetics have a higher risk of developing cerebral vasospasms (CVSP) after subarachnoid hemorrhagic stroke than non-diabetics. Serotonin (5-HT) is one of the key vasoconstrictors released in the hemorrhagic blood and an important contributor to the etiology of CVSP. The combination of the ryanodine...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Román, Marie, García, Laura, Morales, Myrna, Crespo, María J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8110522/
https://ncbi.nlm.nih.gov/pubmed/33972638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-89338-6
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