Role of peripheral 5-HT(5A) receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats

5-HT inhibits cardiac sympathetic neurotransmission in normoglycaemic rats, via 5-HT(1B), 5-HT(1D) and 5-HT(5A) receptor activation. Since type 1 diabetes impairs the cardiac sympathetic innervation leading to cardiopathies, this study aimed to investigate whether the serotonergic influence on cardi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: García-Pedraza, José Ángel, Hernández-Abreu, Oswaldo, Morán, Asunción, Carretero, José, García-Domingo, Mónica, Villalón, Carlos M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7652863/
https://ncbi.nlm.nih.gov/pubmed/33168874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76298-6
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