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Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats

Diabetics have a higher risk of developing cerebral vasospasms (CVSP) than nondiabetics. The addition of the ryanodine receptor (RyR) blocker dantrolene to standard therapies reduces vasospasms in nondiabetics. Whether diabetics with CVSP also benefit from this drug, however, is unknown. We evaluate...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Endocrinol
Hauptverfasser: Crespo, Maria J., Roman, Marie, Matias, Jonathan, Morales, Myrna, Torres, Hector, Quidgley, Jose
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933070/
https://ncbi.nlm.nih.gov/pubmed/29849627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9790303
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