Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats

Diabetics have a higher risk of developing cerebral vasospasms (CVSP) than nondiabetics. The addition of the ryanodine receptor (RyR) blocker dantrolene to standard therapies reduces vasospasms in nondiabetics. Whether diabetics with CVSP also benefit from this drug, however, is unknown. We evaluate...

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Detalhes bibliográficos
Publicado no:Int J Endocrinol
Main Authors: Crespo, Maria J., Roman, Marie, Matias, Jonathan, Morales, Myrna, Torres, Hector, Quidgley, Jose
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933070/
https://ncbi.nlm.nih.gov/pubmed/29849627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9790303
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