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Synergistic Effects of Dantrolene and Nimodipine on the Phenylephrine-Induced Contraction and ACh-Induced Relaxation in Aortic Rings from Diabetic Rats

Diabetics have a higher risk of developing cerebral vasospasms (CVSP) than nondiabetics. The addition of the ryanodine receptor (RyR) blocker dantrolene to standard therapies reduces vasospasms in nondiabetics. Whether diabetics with CVSP also benefit from this drug, however, is unknown. We evaluate...

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Dettagli Bibliografici
Pubblicato in:Int J Endocrinol
Autori principali: Crespo, Maria J., Roman, Marie, Matias, Jonathan, Morales, Myrna, Torres, Hector, Quidgley, Jose
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5933070/
https://ncbi.nlm.nih.gov/pubmed/29849627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9790303
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