Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

BACKGROUND: Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the past decades, prompting the development of inno...

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Udgivet i:J Immunother Cancer
Main Authors: Arnone, Claudia Manuela, Polito, Vinicia Assunta, Mastronuzzi, Angela, Carai, Andrea, Diomedi, Francesca Camassei, Antonucci, Laura, Petrilli, Lucia Lisa, Vinci, Maria, Ferrari, Francesco, Salviato, Elisa, Scarsella, Marco, De Stefanis, Cristiano, Weber, Gerrit, Quintarelli, Concetta, De Angelis, Biagio, Brenner, Malcolm K, Gottschalk, Stephen, Hoyos, Valentina, Locatelli, Franco, Caruana, Ignazio, Del Bufalo, Francesca
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
Fag:
Oncolytic and Local Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108682/
https://ncbi.nlm.nih.gov/pubmed/33963009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001930
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