Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas

BACKGROUND: Pediatric high-grade gliomas (pHGGs) are among the most common and incurable malignant neoplasms of childhood. Despite aggressive, multimodal treatment, the outcome of children with high-grade gliomas has not significantly improved over the past decades, prompting the development of inno...

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Publicado en:J Immunother Cancer
Autores principales: Arnone, Claudia Manuela, Polito, Vinicia Assunta, Mastronuzzi, Angela, Carai, Andrea, Diomedi, Francesca Camassei, Antonucci, Laura, Petrilli, Lucia Lisa, Vinci, Maria, Ferrari, Francesco, Salviato, Elisa, Scarsella, Marco, De Stefanis, Cristiano, Weber, Gerrit, Quintarelli, Concetta, De Angelis, Biagio, Brenner, Malcolm K, Gottschalk, Stephen, Hoyos, Valentina, Locatelli, Franco, Caruana, Ignazio, Del Bufalo, Francesca
Formato: Artigo
Lenguaje:Inglês
Publicado: BMJ Publishing Group 2021
Materias:
Oncolytic and Local Immunotherapy
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8108682/
https://ncbi.nlm.nih.gov/pubmed/33963009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001930
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